Document Type : Original Article


1 Department of Botany, Alagappa University, Science Block, Karaikudi-630 003, India

2 Department of Biotechnology, Vysya College, Salem- 636 103.Tamil Nadu, India


The medicinal plant residue obtained to synthesis AgNPs is the thrust area of research today. The present research work emphasis on the AgNPs synthesized from a medicinal plant residue Artocarpus altilis whose secondary metabolites bear responsible for the confined size of the AgNPs. Further, the AgNPs were analyzed for Physico-chemical analysis, where FT-IR Peak value gives the functional groups of A. altilis. FESEM analyses show surface morphology with 44 nm. EDAX analyses of show metal precursor involved in the process. XRD patterns show the crystalline structure. The AgNPs was analysised for the antibacterial assay against five human pathogens. Finally, cyto-toxic activity of AgNPs was analyzed with two human cancer cell lines namely MCF 7 lung cancer cell line and A549 breast cancer cell line. Hence, the novel and eco-friendly AgNPs are safe with its biocompatibility which becomes a promising agent in the biomedical precisely.

Graphical Abstract

Cyto-toxicity and oligodynamic effect of bio-synthesized silver nanoparticles from plant residue of Artocarpus altilis and its spectroscopic analysis


Main Subjects

[1]. Ahmed S., Ahmad M., Swami B.L. J. Adv. Res., 2016, 7:17
[2]. Rai M.K., Deshmukh S.D., Ingle A.P., Gade A.K. J Appl Microbiol. 2012, 112:841
[3]. Anasane N., Golinska P., Wypij M., Rathod D., Dahm H., Rai M. Mycoses, 2016, 59:157
[4]. Wypij M., Golinska P., Dahm H., Rai M. IET Nanobiotechnol, 2017, 11:336
[5]. Song J.Y., Kim B.S. Bioprocess and Biosystems Engineering, 2009, 32:79
[6]. Briley-Saebo K., Bjørnerud A., Grant D., Ahlstrom H., Berg T., Kindberg G.M. Cell Tissue Res., 2004, 316:315
[7]. Gupta A.K., Gupta M. Biomaterials, 2005, 26:3995
[8]. Schütt W., Grüttner C., Häfeli U.O., Zborowski M., Teller J., Putzar H. Hybridoma, 1997, 16:109
[9]. Mahmoudi M., Simchi A., Milani A.S., Stroeve P. J. Colloid Interface Sci., 2009, 336:510
[10]. Chandra Sekhar E., Krishna Rao K.S.V., Madhu Sudana Rao K., Bahadur Alisha S. Journal of Applied Pharmaceutical Science, 2018, 8:073
[11]. Jayasree L., Janakiram P., Madhavi R. J. World Aquacult Soc., 2006, 37:523
[12]. Kim S., Ryu D.Y. J. Appl. Toxicol.,  2013, 33:78
[13]. Mallick K., Witcomb M.J. Scurrell M.S. Mater. Chem. Phys., 2005, 90:221
[14]. Kovács D., Szke K., Igaz N., Spengler G., Molnár J., Tóth T., Madarás D., Rázga Z., Kónya Z., BorosKiricsi I.M. Nanomedicine, 2016, 12:601
[15]. Mala R., Ruby Celsia A.S., Malathi Devi S., Geerthika S. Materials Science and Engineering, 2017, 225:12155
[16]. Charbgoo F., Ahmad M.B., Darroudi M. Int. J. Nanomed., 2017, 12:1401
[17]. Allafchian A., Jalali S.A.H., Aghaei F., Farhang H.R. IET Nanobiotechnol, 2018, 12:1
[18]. Khatami M., Heli H., Jahani P.M., Azizi H., Nobre M.A.L. IET Nanobiotechnol, 2017, 11: 709
[19]. Siddiqi K.S., Husen A., Rao R.A.K. J Nanobiotechnol.,2018,16:14
[20]. Jones S.A., Bowler P.G., Walker M., Parsons D. Wound Repair Regen, 2004, 12:288
[21]. Allahverdiyev A.M., Abamor E.S., Bagirova M., Rafailovich M. Fut Microb, 2011, 6:933
[22]. Guzman M., Dille J., Godet S. Nanomedicine, 2012, 8:37
[23]. Reddy N.J., Vali D.N., Rani M., Rani S.S. Mat. Sci. Eng. C., 2014, 34:115
[24]. Kumar S.P., Balachandran C., Duraipandiyan V., Ramasamy D., Ignacimuthu S., Al-Dhabi N.A. Appl Nanosci, 2015, 5:169
[25]. Kanipandian N., Kannan S., Ramesh R., Subramanian P., Thirumurugan R. Mat. Res. Bull., 2014, 49:494
[26]. Mosmann T. J. Immunol Methods, 1983, 65:55