Sami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101Surface potential, fermi level and band gap energy of copper doped magnesium nickel ferrite nanoparticles11411843610.26655/AJNANOMAT.2021.1.1ENGideon OsamongDepartment of Physical Sciences, Chuka University, Chuka, KenyaPaul Kuria KamweruDepartment of Physical Sciences, Chuka University, Chuka, KenyaJoel Mwangi GichumbiDepartment of Physical Sciences, Chuka University, Chuka, KenyaFrancis Gichuki NdirituRegistrar Academic Affairs, Chuka University, Chuka, KenyaJournal Article19991130Optical, electrical, and electronic properties of materials are essential in the fabrication of electronic devices. These properties can be improved through doping and reduction of the size of a material to nanoscale. In this study, copper doped magnesium-nickel (Cu<sub>x</sub>Mg<sub>1-x</sub>NiFe<sub>2</sub>O<sub>4, </sub>for x=0.00, 0.15, 0.30, 0.45, 0.60, 0.75, 1.00) ferrite nanoparticles were synthesized using the citra-gel auto combustion method. The electronic and optical properties were evaluated using the scanning Kelvin probe microscopy (SKPM) and UV-visible, respectively. The UV-visible studies revealed that, the band gap energy was at the range of 3.600-3.750 eV. The band gap was noted to increase with copper content up to x=0.45 which then started to decrease. The undoped sample displayed the lowest band gap energy in comparison with the doped. SKPM analysis exhibited the surface potential in the range 4.361-5.002 eV for the area scan and 4.251-5.006 eV for the line scans for the samples. The sample with x=0.75 showed a positive work function for both area and line scans, and all the others had a negative work function. The doped ferrite exhibited the properties that could be applied in optical devices, storage devices, and recording devices.https://www.ajnanomat.com/article_118436_dd87ecb61e912e1f729c159d7dfb8a62.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101Analysis of structural, and electronic properties of clopidogrel drug adsorption on armchair (5, 5) Single-walled carbon nanotube153011924110.26655/AJNANOMAT.2021.1.2ENSeyyed Ahmad HosseiniDepartment of Nanotechnology, Graduate University of Advanced Technology, Kerman, P.O.Box 76315-117 , IranFahimeh ShojaieSemiconductors Group, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, P.O.Box 76315-117 , IranDariush AfzaliDepartment of Environment, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, P.O.Box 76315-117 , IranJournal Article20200817Single-walled carbon nanotubes (SWCNTs) have been widely utilized in many types of applications, cinfirming their excellent role as carriers of drugs with a highly site-selective delivery capability. As nanotubes can release drugs into the tissue cells without damaging the healthy cells, it is necessary to determine the structural properties of drugs–SWCNTs complexes which may lead to the development of optimal SWCNTs as new effective drug transporters. In this work, a theoretical study of structural properties and reactivity of clopidogrel drug with C (5, 5) carbon nanotubes is presented. Computational and chemical simulations were carried out for clopidogrel, SWCNT and clopidogrel-SWCNT by B3LYP/6-31+G with the Gaussian 09 program and then energies of all optimized configurations were evaluated by the M06-2X density functional method. The highest occupied molecular orbital (HOMO), lowest unoccupied molecular orbital (LUMO), natural bond orbital (NBO), global reactivity descriptors and density of states (DOS) of clopidogrel and SWCNT were calculated. The results show that there is a relationship between the energy gap and the DOS. The nature of interaction and bonding between the clopidogrel and SWCNT is physisorption as the adsorption energy and charge transfer is small, and adsorption distance is large. Generally, the results of our simulation studies demonstrated that, the carbon nanotubes have a high potential to be considered as carriers of clopidogrel in drug delivery systems. Band gaps of clopidogrel-SWCNT complex, which were computed by B3LYP method, are 1.777 and 1.860 eV in gas and the solution phases, respectively. Also, the dipole moment of clopidogrel-SWCNT complex in solution phase is 5.286 Debye, which is higher than the gas phase (3.234 Debye). These results show the effect of the solvent on the complex.https://www.ajnanomat.com/article_119241_dd6dfa1596221034573135464eb8f0f0.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101TiCl3-silica: A recyclable solid support for efficient synthesis of substituted imidazoles314511949510.26655/AJNANOMAT.2021.1.3ENRaju SubbaDepartment of Chemistry, University of North Bengal, District-Darjeeling-734013, IndiaHridoydip Ranjan DasguptaDepartment of Chemistry, University of North Bengal, District-Darjeeling-734013, IndiaBittu SahaDepartment of Chemistry, University of North Bengal, District-Darjeeling-734013, IndiaGyan Chandra PariyarDepartment of Chemistry, University of North Bengal, District-Darjeeling-734013, IndiaAbiral TamangDepartment of Physics, Jadavpur University, Kolkata 700032, IndiaPranab GhoshDepartment of Chemistry, University of North Bengal, District-Darjeeling-734013, IndiaJournal Article20200830In this research study, a library of highly substituted imidazoles were efficiently synthesized from benzil/benzoin, aldehydes and ammonium acetate <em>via</em> multicomponent solvent free one pot protocol on TiCl<sub>3</sub>-silica solid catalyst. The general applicability of the solid support was assessed by the synthesis of wide varieties of imidazole derivatives. TiCl<sub>3</sub>-silica solid catalyst was recycled, reused and found no loss of catalytic activity up to fifth consecutive reaction runs. https://www.ajnanomat.com/article_119495_b46db1a406a2a2e317f7b849108f16ce.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101NiO nanoparticle/1-hexyl-3-methylimidazolium hexafluorophosphate composite for amplification of epinephrine electrochemical sensor465212034510.26655/AJNANOMAT.2021.1.4ENSoheila SaghiriDepartment of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IranMahmoud EbrahimiDepartment of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IranMohammad Reza BozorgmehrDepartment of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, IranJournal Article20201030In this research study, NiO nanoparticle (NiO-NPs) was synthesis using a simple strategy method (chemical precipitation), then it was utilized for amplification of paste electrode (PE) at the presence of paraffin oil and 1-hexyl-3-methylimidazolium hexafluorophosphate (HPF6). NiO nanoparticle was characterized using the transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS) method. The NiO-NPs/HPF6/PE was used as electrochemical sensor for determination of epinephrine in pharmaceutical and urine samples. The sensor improved the oxidation signal of epinephrine about 2.87 times. The pH investigation confirmed that the electro-oxidation of epinephrine was relative to pH changing in the presence two electrons and two protons. The square wave voltammetric investigation showed that the oxidation current of epinephrine has linear relation with its concentration in the range 1.0 nM-300 µM with detection limit 0.5 nM.https://www.ajnanomat.com/article_120345_3918dacc6f7b2a602d5e931e652168b1.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101Effects of fluorodeoxyglucose magnetic nanoparticles on NCI-H727 and SH-SY5Y cancer cells536612061510.26655/AJNANOMAT.2021.1.5ENPerihan UnakEge University, Institute of Nuclear Sciences, Department of Nuclear Applications, Bornova Izmir, 35100, Turkey0000-0002-5464-2987Rumbidzai CherylBudiyoAston University, School of Life and Health Sciences, Aston Triangle, Birmingham, B4 7ET, United KingdomAlex HorsnzkyAston University, School of Life and Health Sciences, Aston Triangle, Birmingham, B4 7ET, United KingdomVolkan YasakciEge University, Institute of Nuclear Sciences, Department of Nuclear Applications, Bornova Izmir, 35100, Turkey0000-0002-4133-3886Gillian PearceSchool of Engineering and Applied Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, United Kingdom0000-0003-1428-2021Steve RussellAston University, School of Life and Health Sciences, Aston Triangle, Birmingham, B4 7ET, United Kingdom0000-0002-5491-900XOmer ArasMemorial Sloan Kettering Cancer Centre, Department of Radiology, New York, USA0000-0003-1758-0542Akin OguzMemorial Sloan Kettering Cancer Centre, Department of Radiology, New York, USA0000-0002-2041-6199Julian WongUniversity Hospital Singapore, Cardiothoracic and Vascular Surgery Department, Singapore0000-0002-9708-9077Journal Article20201009< p>< p>We present a report regarding the cytotoxic effects of iron-based magnetic nanoparticles conjugated with fluorodeoxyglucose (FDG-mNPs) on the viability of NCI-H727 and SH-SY5Y cancer cells. MTT assays were performed to determine cell viability in treated cancer cells grown under standard 2D culture conditions. FDG-mNP concentrations of 0.075 mg/mL, 0.15 mg/mL, and 0.3 mg/mL decreased mean cell viability of NCI-H727 cells to 92.5%, 82.9%, and 75% respectively. FDG-mNPs was also shown to have a detrimental effect on the viability of SY5Y cells: a decrease of 5.7%, 18.6%, and 36.4% was found for SY5Y cells treated with 0.075 mg/mL, 0.15 mg/mL, and 0.3 mg/mL concentrations of FDG-mNPs, respectively. When NCI-H727 and SH-SY5Y cancer cells were grown as 3D spheroids, morphology was visibly changed and the number of viable cells was decerased in spheroids treated with FDG-mNPs compared with untreated spheroids. The results of our study demonstrated that FDG-mNP has toxic effects on NCI-H7272 and SY5Y cancer cells, and we conclude that conjugated FDG-mNPs are promising in the development of clinical applications for the destruction of cancer cells.https://www.ajnanomat.com/article_120615_b4c9eff4f9cab9619bf83734dd49b86c.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4120210101A review of applications and mechanisms nanoparticles on inhibiting the growth of pathogens678012081510.26655/AJNANOMAT.2021.1.6ENNastaran GhandaliDepartment of Biology, Ahvaz Branch, Chamran University, Ahvaz, IranSeyyedeh Masumeh MirnurollahiDepartment of Biology, Faculty of Basic Sciences, University of Central Tehran, Tehran, IranRoya SafarkarDepartment of Biology, Ardabil Branch, Islamic Azad University, Ardabil, IranJournal Article20200924The purpose of this research study was to assess the use of nanoparticles in combat pathogenic microorganisms and also to investigate the synergistic effect of nanoparticles with antibiotics in eliminating these factors. In this work, the influence of different nanoparticles on microorganisms was evaluated in 89 studies. It was found that nanoparticles can be used against microorganisms, either independently or by their synergistic effect with antibiotics. The study found that metal nanoparticles have a more anti-microbial effect, among metal nanoparticles, silver nanoparticles exert the most specific among all microorganisms. Meanwhile, metal nanoparticles can be a good alternative to the use of antibiotics and inhibitors of pathogens.https://www.ajnanomat.com/article_120815_50d41355fb880b071ab54bb4a20fac8c.pdfSami Publishing CompanyAsian Journal of Nanoscience and Materials2645-775X4119991130Synthesis of 5-arylmethylene-pyrimidine-2,4,6-trione and 2-arylidenemalononitriles derivatives using a new Brønsted acid nano magnetic catalyst819412267410.26655/AJNANOMAT.2021.1.7ENKhadijeh YadollahzadehDepartment of Chemistry, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, IranJournal Article19991130In this work, 1-methyl imidazole-based ionic liquid stabilized on silica coated Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles [nano-Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@(CH<sub>2</sub>)<sub>3</sub>-1-methyl imidazole]HSO<sub>4 </sub>as a new, efficient, and magnetic Brønsted acid nano-magnetic catalyst was synthesized and characterized using various techniques including, Fourier transform infrared spectrometer (FT-IR), scanning electron microscopy (SEM), thermo gravimetric analysis (TGA), X-ray diffraction patterns (XRD), and vibrating sample magnetometry (VSM). Magnetic nanoparticles (MNPs) were used to synthesize thr 5-arylmethylene-pyrimidine-2, 4, 6-trione derivatives by the one-pot condensation reaction between barbituric acid and various aldehydes in water at reflux conditions. Similarly, 2-arylidenemalononitriles were synthesized by the one-pot of condensation reaction between various aldehydes and malononitrilein water as a green solvent at room temperature. This method has several advantages, such as short reaction times and high yields, non-using of toxic solvent, being eco-friendly benign, recyclability and reusability of the catalyst with external magnet for several time.https://www.ajnanomat.com/article_122674_2fea208999ebd8a61cc77a6dacdf3716.pdf