Antibacterial activity of magnesium oxide nanostructures prepared by hydrothermal method

Document Type: Original Article

Authors

1 Special Centre for Nanoscience, Department of Physics, NIT Srinagar, J&K, India-190006

2 SSM College of Engineering and Technology, Baramulla, J&K, India-193121

Abstract

In this research study, the magnesium oxide nanoparticles were synthesized using an inexpensive and simple hydrothermal method. A pure magnesium metal powder, de-ionized water, and hydrogen peroxide (H2O2) was utilized as the starting materials. The synthesized MgO was dense, uniformly distributed with a relatively spherical shape, without any cracks and voids as confirmed by the scaning electron microscopy (SEM) analysis. The structure was crystalline with a high purity. No other peak corresponding to any other material or metal could be ascertained from powder X-ray diffraction (XRD) pattern. The crystallite size of the prepared samples was found to be nearly 18 nm which was favorable for antibacterial activity. The antibacterial activity of MgO nanostructures was carried out by using disc diffusion method. The inhibition zones of diameters = 1 mm were observed in case of salmonella and Staphylococcus aureus, however, in case of E. Coli inhibition zones of diameter = 2 mm was obtained.

Graphical Abstract

Antibacterial activity of magnesium oxide nanostructures prepared by hydrothermal method

Keywords

Main Subjects


[1]. Leung Y.H., Ng A.M., Xu X., Shen Z., Gethings L.A., Wong M.T., Lee P.K. Small, 2014, 10:1171

[2]. Krishnamoorthy K., Manivannan G., Kim S.J., Jeyasubramanian K., Premanathan M. Journal of Nanoparticle Research, 2012, 14:1063

[3]. Jin T., He Y. Journal of Nanoparticle Research, 2011, 13:6877

[4]. Bindhu M.R., Umadevi M., Micheal M.K., Arasu M.V., Al-Dhabi N.A. Materials Letters, 2016, 166:19

[5]. Zhu X., Wu D., Wang W., Tan F., Wong P. K., Wang X., Qiao X. Journal of Alloys and Compounds, 2016, 684:282

[6]. Karthik K., Dhanuskodi S., Kumar S.P., Gobinath C., Sivaramakrishnan S. Materials Letters, 2017, 206:217

[7]. Sundrarajan M., Suresh J., Gandhi R.R. Digest journal of nanomaterials and biostructures, 2012, 7:983

[8]. Tang Z.X., Fang  X.J., Zhang Z.L., Zhou T., Zhang X.Y., Shi L.E. Brazilian Journal of Chemical Engineering, 2012, 29:775

[9]. Hirota K., Sugimoto M., Kato M., Tsukagoshi K., Tanigawa T., Sugimoto H. Ceramics International, 2010, 36:497

[10]. Rao Y., Wang W., Tan F., Cai Y., Lu J., Qiao X.  Applied Surface Science, 2013, 284:726

[11]. Ohira T., Kawamura M., Fukuda M., Alvarez K., Özkal B., Yamamoto O. Journal of materials engineering and performance, 2010, 19:374

[12]. Rahman M.S., Rashid M.A. Oriental Pharm. Exp. Med., 2008, 8:47

[13]. Gokulakrishnan R., Ravikumar S., Raj J.A. Asian Pacific Journal of Tropical Disease, 2012, 2:411

[14]. Yamamoto O., Ohira T., Alvarez  K., Fukuda, M. Materials Science and Engineering: B, 2010, 173:208


Articles in Press, Accepted Manuscript
Available Online from 08 June 2019
  • Receive Date: 14 December 2018
  • Revise Date: 06 May 2019
  • Accept Date: 07 May 2019