%0 Journal Article %T Embedded Ag NPs in Cysteine-Poly (acrylic acid) Hydrogel with Antibacterial Activity %J Asian Journal of Nanoscience and Materials %I Sami Publishing Company %Z 2645-775X %A Fathalipour, Soghra %A Ghanbarizadeh, Mahdiye %D 2019 %\ 01/01/2019 %V 2 %N 1 %P 37-48 %! Embedded Ag NPs in Cysteine-Poly (acrylic acid) Hydrogel with Antibacterial Activity %K hydrogels %K Composites %K antibacterial %K inorganic materials %K Ag NPs %R 10.26655/ajnanomat.2019.1.3 %X In this research,Ag NPs were loaded on cysteine modified poly(acrylic acid) (PAA) hydrogel. Obtainedcysteine-hydrogel (Chydrogel) having different functional groups could stabilize Ag NPs better than un-modified hydrogel due to the presence of disulfid bondings. First, obtained PAA hydrogel from radical polymerization was conjugated with cysteine-hydrochloride (Cys) through amidation reaction and then was used as a substrate and stabilization reagent for Ag ions. Ag ions were reduced on Chydrogel in the presence ofNaBH4 as reducing reagent. The resultant nanocomposite was well characterized by using UV–vis, FT-IR, XRD and SEM techniques. Furthermore, the resultant Ag NPs on the surface of Chydrogel showedhigh antibacterial behavior against Gram-negative E. coliand Gram-positive S. aureusdue to the high reaction of thiol-functions with the outer cell surface. %U https://www.ajnanomat.com/article_73762_575158cc3cf3fcd85ba3df0bc973b90a.pdf